Adiponectin protects obesity-related glomerulopathy by inhibiting ROS/NF-κB/NLRP3 inflammation pathway

Adiponectin protects obesity-related glomerulopathy by inhibiting ROS/NF-κB/NLRP3 inflammation pathway

Abstract Background Adiponectin is an adipocytokine that plays a key regulatory role in glucose and lipid metabolism in obesity. The prevalence of obesity has led to an increase in the incidence of obesity-related glomerulopathy (ORG). This study aimed to identify the protective role of adiponectin...

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Bibliographic Details
Main Authors: Xiaohong Xu, Xiaolin Huang, Liexiang Zhang, Xiaoli Huang, Zihan Qin, Fei Hua
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Nephrology
Subjects:
Adiponectin
Obesity-related glomerulopathy
ROS
NF-κB
NLRP3 inflammation
Online Access:https://doi.org/10.1186/s12882-021-02391-1

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