Dual <i>Mkk4</i> and <i>Mkk7</i> Gene Deletion in Adult Mouse Causes an Impairment of Hippocampal Immature Granule Cells

Dual <i>Mkk4</i> and <i>Mkk7</i> Gene Deletion in Adult Mouse Causes an Impairment of Hippocampal Immature Granule Cells

(1) Background: The c-Jun-NH2-terminal protein kinase (JNK) is a mitogen-activated protein kinase involved in regulating physiological processes in the central nervous system. However, the dual genetic deletion of <i>Mkk4</i> and <i>Mkk7</i> (upstream activators of JNK) in ad...

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Bibliographic Details
Main Authors: Rubén Darío Castro-Torres, Jordi Olloquequi, Miren Etchetto, Pablo Caruana, Luke Steele, Kyra-Mae Leighton, Jesús Ureña, Carlos Beas-Zarate, Antoni Camins, Ester Verdaguer, Carme Auladell
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
Cre-LoxP
MKK4
MKK7
pJNK
DCX
hippocampus
Online Access:https://www.mdpi.com/1422-0067/22/17/9545

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