Lyell’s syndrome in children – clinical features, treatment

Lyell’s syndrome is one of the most serious diseases of a toxic-allergic nature and it presents a real threat to children life. The article presents literature data and clinical observations of Lyell’s syndrome in children, the etiological cause of which was medication, often used in pediatric pract...

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Bibliographic Details
Main Authors: G. A. Kharchenko, O. G. Kimirilova
Format: Article
Language:Russian
Published: Ltd. “The National Academy of Pediatric Science and Innovation” 2019-03-01
Series:Rossijskij Vestnik Perinatologii i Pediatrii
Subjects:
Online Access:https://www.ped-perinatology.ru/jour/article/view/824
Description
Summary:Lyell’s syndrome is one of the most serious diseases of a toxic-allergic nature and it presents a real threat to children life. The article presents literature data and clinical observations of Lyell’s syndrome in children, the etiological cause of which was medication, often used in pediatric practice for viral infections – 0.05% eye bonafton ointment, paracetamol. Based on the analysis of literature data and our own observations, we propose the algorithm of therapeutic measures in children with Lyell’s syndrome, which includes the administration of glucocorticoids, immunoglobulins for intravenous administration, hyposensitizing agents, correction of water and electrolyte balance, local treatment, etc.
ISSN:1027-4065
2500-2228