ALDH1A3 Is the Key Isoform That Contributes to Aldehyde Dehydrogenase Activity and Affects in Vitro Proliferation in Cardiac Atrial Appendage Progenitor Cells

ALDH1A3 Is the Key Isoform That Contributes to Aldehyde Dehydrogenase Activity and Affects in Vitro Proliferation in Cardiac Atrial Appendage Progenitor Cells

High aldehyde dehydrogenase (ALDHhi) activity has been reported in normal and cancer stem cells. We and others have shown previously that human ALDHhi cardiac atrial appendage cells are enriched with stem/progenitor cells. The role of ALDH in these cells is poorly understood but it may come down to...

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Bibliographic Details
Main Authors: Stefania Puttini, Isabelle Plaisance, Lucio Barile, Elisabetta Cervio, Giuseppina Milano, Paola Marcato, Thierry Pedrazzini, Giuseppe Vassalli
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
aldehyde dehydrogenase
ALDH1A3
cardiac progenitor cell
stem cell
heart
Online Access:https://www.frontiersin.org/article/10.3389/fcvm.2018.00090/full

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