5-Aryl-1-Arylideneamino-1<i>H</i>-Imidazole<i>-</i>2(3H)-Thiones: Synthesis and in Vitro Anticancer Evaluation

5-Aryl-1-Arylideneamino-1<i>H</i>-Imidazole<i>-</i>2(3H)-Thiones: Synthesis and in Vitro Anticancer Evaluation

A novel series of <i>N-1</i> arylidene amino imidazole-2-thiones were synthesized, identified using IR, <sup>1</sup>H-NMR, and <sup>13</sup>C-NMR spectral data. Cytotoxic effect of the prepared compounds was carried out utilizing three cancer cell lines; MCF-7 bre...

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Bibliographic Details
Main Authors: Ali H. Abu Almaaty, Eslam E. M. Toson, El-Sherbiny H. El-Sayed, Mohamed A. M. Tantawy, Eman Fayad, Ola A. Abu Ali, Islam Zaki
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Molecules
Subjects:
imidazole
synthesis
cytotoxicity
apoptosis
cell cycle analysis
Annexin V
Online Access:https://www.mdpi.com/1420-3049/26/6/1706

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