A New Method to Model and Predict Progression Free Survival Based on Tumor Growth Dynamics

Progression‐free survival (PFS) has been increasingly used as a primary endpoint for early clinical development. The aim of the present work was to develop a model where target lesion dynamics and risk for nontarget progression are jointly modeled for predicting PFS. The model was developed based on...

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Bibliographic Details
Main Authors: Jiajie Yu, Nina Wang, Matts Kågedal
Format: Article
Language:English
Published: Wiley 2020-03-01
Series:CPT: Pharmacometrics & Systems Pharmacology
Online Access:https://doi.org/10.1002/psp4.12499