Single-Molecule Insights Into the Dynamics of Replicative Helicases

Helicases are molecular motors that translocate along single-stranded DNA and unwind duplex DNA. They rely on the consumption of chemical energy from nucleotide hydrolysis to drive their translocation. Specialized helicases play a critically important role in DNA replication by unwinding DNA at the...

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Bibliographic Details
Main Authors: Richard R. Spinks, Lisanne M. Spenkelink, Nicholas E. Dixon, Antoine M. van Oijen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.741718/full