Prioritization of genetic variants predisposing to coronary heart disease in the Bulgarian population using centenarian exomes

Prioritization of genetic variants predisposing to coronary heart disease in the Bulgarian population using centenarian exomes

Coronary heart disease (CHD) is a major cause of mortality and morbidity in Europe. CHD is usually caused by atherosclerosis. Despite extensive studies that have identified a large number of genetic variants, strong evidence of association with CHD are not easily replicable in different populations....

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Bibliographic Details
Main Authors: Mihail Ganev, Lubomir Balabanski, Dimitar Serbezov, Sena Karachanak-Yankova, Radoslava Vazharova, Desislava Nesheva, Zora Hammoudeh, Dragomira Nikolova, Olga Antonova, Rada Staneva, Marta Mihaylova, Vera Damyanova, Savina Hadjidekova, Draga Toncheva
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Biotechnology & Biotechnological Equipment
Subjects:
coronary heart disease associated variants
whole-exome sequencing
centenarians
bulgarian
Online Access:http://dx.doi.org/10.1080/13102818.2019.1700164

Internet

http://dx.doi.org/10.1080/13102818.2019.1700164

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