Crosstalks between integrin alpha 5 and IGF2/IGFBP2 signalling trigger human bone marrow-derived mesenchymal stromal osteogenic differentiation

<p>Abstract</p> <p>Background</p> <p>The potential of mesenchymal stromal cells (MSCs) to differentiate into functional bone forming cells provides an important tool for bone regeneration. The identification of factors that trigger osteoblast differentiation in MSCs is...

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Bibliographic Details
Main Authors: Ringe Jochen, Fromigué Olivia, Hamidouche Zahia, Häupl Thomas, Marie Pierre J
Format: Article
Language:English
Published: BMC 2010-06-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/11/44