Comparing 2-nt 3' overhangs against blunt-ended siRNAs: a systems biology based study
<p>Abstract</p> <p>In this study, we formulate a computational reaction model following a chemical kinetic theory approach to predict the binding rate constant for the siRNA-RISC complex formation reaction. The model allowed us to study the potency difference between 2-nt 3' o...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2009-07-01
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| Series: | BMC Genomics |