Cutaneous and Gastrointestinal Symptoms in Two Patients with Systemic Mastocytosis Successfully Treated with Omalizumab

Cutaneous and Gastrointestinal Symptoms in Two Patients with Systemic Mastocytosis Successfully Treated with Omalizumab

The pathogenesis of mastocytosis is not well defined and thus treatment remains challenging and remains on a palliative basis. We present two cases (a 48-year-old woman and a 57-year-old man) with indolent systemic mastocytosis in whom omalizumab (anti-IgE) reduced gastrointestinal and cutaneous sym...

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Main Authors: Sofie Lieberoth, Simon Francis Thomsen
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2015/903541
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spelling doaj-bad30662494c429d83df461ea1c4e2ae2020-11-24T23:04:23ZengHindawi LimitedCase Reports in Medicine1687-96271687-96352015-01-01201510.1155/2015/903541903541Cutaneous and Gastrointestinal Symptoms in Two Patients with Systemic Mastocytosis Successfully Treated with OmalizumabSofie Lieberoth0Simon Francis Thomsen1Department of Dermatology, Bispebjerg Hospital, 2400 Copenhagen NV, DenmarkDepartment of Dermatology, Bispebjerg Hospital, 2400 Copenhagen NV, DenmarkThe pathogenesis of mastocytosis is not well defined and thus treatment remains challenging and remains on a palliative basis. We present two cases (a 48-year-old woman and a 57-year-old man) with indolent systemic mastocytosis in whom omalizumab (anti-IgE) reduced gastrointestinal and cutaneous symptoms significantly. This observation provides additional insight into the effects of omalizumab on systemic mastocytosis.http://dx.doi.org/10.1155/2015/903541
collection DOAJ
language English
format Article
sources DOAJ
author Sofie Lieberoth
Simon Francis Thomsen
spellingShingle Sofie Lieberoth
Simon Francis Thomsen
Cutaneous and Gastrointestinal Symptoms in Two Patients with Systemic Mastocytosis Successfully Treated with Omalizumab
Case Reports in Medicine
author_facet Sofie Lieberoth
Simon Francis Thomsen
author_sort Sofie Lieberoth
title Cutaneous and Gastrointestinal Symptoms in Two Patients with Systemic Mastocytosis Successfully Treated with Omalizumab
title_short Cutaneous and Gastrointestinal Symptoms in Two Patients with Systemic Mastocytosis Successfully Treated with Omalizumab
title_full Cutaneous and Gastrointestinal Symptoms in Two Patients with Systemic Mastocytosis Successfully Treated with Omalizumab
title_fullStr Cutaneous and Gastrointestinal Symptoms in Two Patients with Systemic Mastocytosis Successfully Treated with Omalizumab
title_full_unstemmed Cutaneous and Gastrointestinal Symptoms in Two Patients with Systemic Mastocytosis Successfully Treated with Omalizumab
title_sort cutaneous and gastrointestinal symptoms in two patients with systemic mastocytosis successfully treated with omalizumab
publisher Hindawi Limited
series Case Reports in Medicine
issn 1687-9627
1687-9635
publishDate 2015-01-01
description The pathogenesis of mastocytosis is not well defined and thus treatment remains challenging and remains on a palliative basis. We present two cases (a 48-year-old woman and a 57-year-old man) with indolent systemic mastocytosis in whom omalizumab (anti-IgE) reduced gastrointestinal and cutaneous symptoms significantly. This observation provides additional insight into the effects of omalizumab on systemic mastocytosis.
url http://dx.doi.org/10.1155/2015/903541
work_keys_str_mv AT sofielieberoth cutaneousandgastrointestinalsymptomsintwopatientswithsystemicmastocytosissuccessfullytreatedwithomalizumab
AT simonfrancisthomsen cutaneousandgastrointestinalsymptomsintwopatientswithsystemicmastocytosissuccessfullytreatedwithomalizumab
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