Differential Expression of Complement Markers in Normal and AMD Transmitochondrial Cybrids.

Differential Expression of Complement Markers in Normal and AMD Transmitochondrial Cybrids.

Variations in mitochondrial DNA (mtDNA) and abnormalities in the complement pathways have been implicated in the pathogenesis of age-related macular degeneration (AMD). This study was designed to determine the effects of mtDNA from AMD subjects on the complement pathway.Transmitochondrial cybrids we...

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Bibliographic Details
Main Authors:	Sonali Nashine, Marilyn Chwa, Mina Kazemian, Kunal Thaker, Stephanie Lu, Anthony Nesburn, Baruch D Kuppermann, M Cristina Kenney
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2016-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC4972370?pdf=render

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