Crystal Structure of the Human Ribosome in Complex with DENR-MCT-1

Crystal Structure of the Human Ribosome in Complex with DENR-MCT-1

The repertoire of the density-regulated protein (DENR) and the malignant T cell-amplified sequence 1 (MCT-1/MCTS1) oncoprotein was recently expanded to include translational control of a specific set of cancer-related mRNAs. DENR and MCT-1 form the heterodimer, which binds to the ribosome and operat...

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Bibliographic Details
Main Authors: Ivan B. Lomakin, Elena A. Stolboushkina, Anand T. Vaidya, Chenguang Zhao, Maria B. Garber, Sergey E. Dmitriev, Thomas A. Steitz
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Cell Reports
Subjects:
ribosome
protein synthesis
translation initiation
translation reinitiation
density regulated protein
malignant T cell-amplified sequence 1
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717308227

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http://www.sciencedirect.com/science/article/pii/S2211124717308227

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