Glutamine metabolism regulates autophagy-dependent mTORC1 reactivation during amino acid starvation

Glutamine metabolism regulates autophagy-dependent mTORC1 reactivation during amino acid starvation

mTORC1 is a critical kinase that regulates cell growth and proliferation. Here the authors show that glutamine metabolism is sufficient to restore mTORC1 activity during prolonged amino acid starvation in an autophagy-dependent manner.

Bibliographic Details
Main Authors: Hayden Weng Siong Tan, Arthur Yi Loong Sim, Yun Chau Long
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00369-y

Internet

https://doi.org/10.1038/s41467-017-00369-y

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