Combined transcriptomic and lipidomic analysis reveals aberrant lipid metabolism in central nervous system hemangioblastomas

Abstract Peritumoral cysts are commonly detected in the central nervous system tumors, especially hemangioblastomas (HBs). However, the molecular mechanisms driving their formation and propagation are still unknown. We conducted an integrated lipidomics and transcriptomics analysis on solid and cyst...

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Bibliographic Details
Main Authors: Qiguang Wang, Wenke Liu, Si Zhang, Zuoyu Liang, Linhong Jiang, Aiqin Xue, Xiaobo Cen, Qian Bu
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-80263-8