Sphere culture of murine lung cancer cell lines are enriched with cancer initiating cells.

Sphere culture of murine lung cancer cell lines are enriched with cancer initiating cells.

Cancer initiating cells (CICs) represent a unique cell population essential for the maintenance and growth of tumors. Most in vivo studies of CICs utilize human tumor xenografts in immunodeficient mice. These models provide limited information on the interaction of CICs with the host immune system a...

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Bibliographic Details
Main Authors:	Brian J Morrison, Jason C Steel, John C Morris
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2012-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3496706?pdf=render

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