Nr2e1 Deficiency Augments Palmitate-Induced Oxidative Stress in Beta Cells

Nr2e1 Deficiency Augments Palmitate-Induced Oxidative Stress in Beta Cells

Nuclear receptor subfamily 2 group E member 1 (Nr2e1) has been regarded as an essential regulator of the growth of neural stem cells. However, its function elsewhere is unknown. In the present study, we generated Nr2e1 knockdown MIN6 cells and studied whether Nr2e1 knockdown affected basal beta cell...

Full description

Bibliographic Details
Main Authors:	Xiaoli Shi, Haohua Deng, Zhe Dai, Yancheng Xu, Xiaokan Xiong, Pei Ma, Jing Cheng
Format:	Article
Language:	English
Published:	Hindawi Limited 2016-01-01
Series:	Oxidative Medicine and Cellular Longevity
Online Access:	http://dx.doi.org/10.1155/2016/9648769

Similar Items

Augmentation of Glucotoxicity, Oxidative Stress, Apoptosis and Mitochondrial Dysfunction in HepG2 Cells by Palmitic Acid
by: Arwa Alnahdi, et al.
Published: (2019-08-01)

UPR in palmitate-treated pancreatic beta-cells is not affected by altering oxidation of the fatty acid
by: Sol E-ri, et al.
Published: (2011-10-01)

Incorporation of [U-14C]palmitate into rat brain: effect of an inhibitor of beta-oxidation
by: M C Chang, et al.
Published: (1997-02-01)

Molecular Mechanisms of Palmitic Acid Augmentation in COVID-19 Pathologies
by: Christie Joshi, et al.
Published: (2021-07-01)

T cells cooperate with palmitic acid in induction of beta cell apoptosis
by: Miljković Djordje, et al.
Published: (2009-05-01)

Beta-cyclodextrin functionalized cellulose nanofiber for the removal of palmitic acid
by: Mohd. Shah, Nurul Aqilah
Published: (2020)

High beta-palmitate fat controls the intestinal inflammatory response and limits intestinal damage in mucin Muc2 deficient mice.
by: Peng Lu, et al.
Published: (2013-01-01)

The role of palmitate in skeletal muscle cell insulin resistance and pancreatic beta cell dysfunction
by: Watson, Maria
Published: (2009)

Antioxidant effect of mogrosides against oxidative stress induced by palmitic acid in mouse insulinoma NIT-1 cells
by: Q. Xu, et al.
Published: (2013-11-01)

Curcumin Ameliorates Palmitic Acid-Induced Saos-2 Cell Apoptosis Via Inhibiting Oxidative Stress and Autophagy
by: Baicheng Ma, et al.
Published: (2021-01-01)

Beta Palmitate Improves Bone Length and Quality during Catch-Up Growth in Young Rats
by: Meytal Bar-Maisels, et al.
Published: (2017-07-01)

Polysiphonia japonica Extract Attenuates Palmitate-Induced Toxicity and Enhances Insulin Secretion in Pancreatic Beta-Cells
by: Seon-Heui Cha, et al.
Published: (2018-01-01)

Role of circulating levels of palmitate and palmitoleate in development of beta cell dysfunction and insulin resistance in pediatric obesity
by: Staaf, Johan
Published: (2011)

Palmitic and linoleic acids induce ER stress and apoptosis in hepatoma cells
by: Zhang Yong, et al.
Published: (2012-01-01)

The 'Cis-' and 'Trans-' Biosynthesis of Palmitic Acid Esters by Esterification of Palmitic Acid with Methanol or Ethanol
by: TSENG, YU-WEI, et al.
Published: (2018)

Water-phase palmitate concentrations in equilibrium with albumin-bound palmitate in a biological system.
by: IN Bojesen, et al.
Published: (1992-09-01)

Study on the encapsulation of ascorbyl palmitate in solid lipid nanoparticles
by: Pei-chun Ro, et al.
Published: (2007)

Beta-Ketothiolase Deficiency
by: Elsayed Abdelkreem MD, MSc, et al.
Published: (2016-03-01)

Paliperidone palmitate-induced sialorrhoea
by: Cengiz Cengisiz, et al.
Published: (2016-03-01)

Accidental Overdose of Paliperidone Palmitate
by: Chiedozie Ojimba, et al.
Published: (2019-01-01)

PROSPECTS OF APPLICATION OF A MIXTURE BASED ON GOAT MILK WITH BETA-PALMITIC ACID IN CHILDREN THE FIRST YEAR OF LIFE
by: O. N. Komarova, et al.
Published: (2017-12-01)

The Distinct Effects of Palmitic and Oleic Acid on Pancreatic Beta Cell Function: The Elucidation of Associated Mechanisms and Effector Molecules
by: Miruna Nemecz, et al.
Published: (2019-01-01)

The Class I Histone Deacetylase Inhibitor MS-275 Prevents Pancreatic Beta Cell Death Induced by Palmitate
by: Valérie Plaisance, et al.
Published: (2014-01-01)

Effects of NR1 splicing on NR1/NR3B-type excitatory glycine receptors
by: Orth Angela, et al.
Published: (2009-04-01)

The Functional Roles of Palmitic Acid in Glioblastoma Multiforme Cells
by: XIE, JING-YU, et al.
Published: (2018)

A Comparison of Retinyl Palmitate and Red Palm Oil β-Carotene as Strategies to Address Vitamin A Deficiency
by: Regina Moench-Pfanner, et al.
Published: (2013-08-01)

N.R.
Published: (2010-01-01)

Oxidative stress as a treatment target in atopic dermatitis: The role of furfuryl palmitate in mild-to-moderate atopic dermatitis
by: Adelaide A. Hebert, MD
Published: (2020-09-01)

Hardware Sharing for Channel Interleavers in 5G NR Standard
by: Xiaokang Xiong, et al.
Published: (2021-01-01)

Effect of cis- and trans-Monounsaturated Fatty Acids on Palmitate Toxicity and on Palmitate-induced Accumulation of Ceramides and Diglycerides
by: Farkas Sarnyai, et al.
Published: (2020-04-01)

Chronic effects of palmitate overload on nutrient-induced insulin secretion and autocrine signalling in pancreatic MIN6 beta cells.
by: Maria L Watson, et al.
Published: (2011-01-01)

Dopamine beta-hydroxylase deficiency
by: Senard Jean-Michel, et al.
Published: (2006-03-01)

Mdivi-1 Protects Adult Rat Hippocampal Neural Stem Cells against Palmitate-Induced Oxidative Stress and Apoptosis
by: Sehee Kim, et al.
Published: (2017-09-01)

Pharmacokinetics and in vitro stability of retinyl palmitate
by: Einspahr, Janine Gay
Published: (1981)

Palmitate Activation and Esterification in Rat Liver
by: Lloyd-Davies, K. A.
Published: (1974)

Stable isotope dilution method for measurement of palmitate content and labeled palmitate tracer enrichment in microliter plasma samples.
by: P F Bougnères, et al.
Published: (1982-03-01)

Distinct expression of synaptic NR2A and NR2B in the central nervous system and impaired morphine tolerance and physical dependence in mice deficient in postsynaptic density-93 protein
by: Johns Roger A, et al.
Published: (2008-10-01)

Reduced Graphene Oxide/Gold Nanoparticles Modified Screen-Printed Electrode for the Determination of Palmitic Acid
by: Chin Boon Ching, et al.
Published: (2021-01-01)

Increased palmitate intake: higher acylcarnitine concentrations without impaired progression of β-oxidation1[S]
by: C.Lawrence Kien, et al.
Published: (2015-09-01)

Acetate Does Not Affect Palmitate Oxidation and AMPK Phosphorylation in Human Primary Skeletal Muscle Cells
by: Manuel A. González Hernández, et al.
Published: (2021-06-01)