Comparison of quantitative real-time PCR and direct immunofluorescence for the detection of Pneumocystis jirovecii.

Comparison of quantitative real-time PCR and direct immunofluorescence for the detection of Pneumocystis jirovecii.

Pneumocystis pneumonia (PCP) is a serious risk for HIV-positive patients. Asymptomatic infection or colonisation with P. jirovecii has been shown to occur frequently. PCR assays frequently identify such cases, due to their high sensitivity. Quantitative real-time PCR (qPCR) gene copy number cut-off...

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Bibliographic Details
Main Authors: Bhavani Moodley, Stefano Tempia, John Andrew Frean
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5500343?pdf=render

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