Halogenated Anesthetics Determination in Urine by SPME/GC/MS and Urine Levels Relationship Evaluation with Surgical Theatres Contamination

Halogenated Anesthetics Determination in Urine by SPME/GC/MS and Urine Levels Relationship Evaluation with Surgical Theatres Contamination

In this work, a new sensitive analytical method has been developed and evaluated for the determination of the most commonly used gaseous anesthetics, desflurane, sevoflurane, and this latter’s hepatic metabolite hexafluoroisopropanol (HFIP) in the urine. In addition, an evaluation of anesthetics exp...

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Main Authors: Serena Indelicato, David Bongiorno, Sergio Indelicato, Leopoldo Ceraulo, Ernesto Tranchina, Giuseppe Avellone, Concetta Arcadipane, Filippo Giambartino
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Journal of Analytical Methods in Chemistry
Online Access:http://dx.doi.org/10.1155/2014/753237
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spelling doaj-ba8032d9d6f5472080ed595f4e103b342020-11-25T00:59:44ZengHindawi LimitedJournal of Analytical Methods in Chemistry2090-88652090-88732014-01-01201410.1155/2014/753237753237Halogenated Anesthetics Determination in Urine by SPME/GC/MS and Urine Levels Relationship Evaluation with Surgical Theatres ContaminationSerena Indelicato0David Bongiorno1Sergio Indelicato2Leopoldo Ceraulo3Ernesto Tranchina4Giuseppe Avellone5Concetta Arcadipane6Filippo Giambartino7Dipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche (STEBICEF), Università Degli Studi di Palermo, Via Archirafi 32, 90123 Palermo, ItalyDipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche (STEBICEF), Università Degli Studi di Palermo, Via Archirafi 32, 90123 Palermo, ItalyCQRC Laboratory, A.O.U.P. “P. Giaccone”, Via del Vespro 129, 90127 Palermo, ItalyDipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche (STEBICEF), Università Degli Studi di Palermo, Via Archirafi 32, 90123 Palermo, ItalyDipartimento di Scienze per la Promozione della Salute e Materno Infantile “G.D’Alessandro”, Sezione di Medicina del Lavoro, Via del Vespro, 90127 Palermo, ItalyDipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche (STEBICEF), Università Degli Studi di Palermo, Via Archirafi 32, 90123 Palermo, ItalyDipartimento di Scienze per la Promozione della Salute e Materno Infantile “G.D’Alessandro”, Sezione di Medicina del Lavoro, Via del Vespro, 90127 Palermo, ItalyDipartimento di Biopatologia e Biotecnologie Mediche e Forensi, Via del Vespro, 90127 Palermo, ItalyIn this work, a new sensitive analytical method has been developed and evaluated for the determination of the most commonly used gaseous anesthetics, desflurane, sevoflurane, and this latter’s hepatic metabolite hexafluoroisopropanol (HFIP) in the urine. In addition, an evaluation of anesthetics exposition on the urine levels of a small population of surgical operators has been performed and results are briefly discussed.http://dx.doi.org/10.1155/2014/753237
collection DOAJ
language English
format Article
sources DOAJ
author Serena Indelicato
David Bongiorno
Sergio Indelicato
Leopoldo Ceraulo
Ernesto Tranchina
Giuseppe Avellone
Concetta Arcadipane
Filippo Giambartino
spellingShingle Serena Indelicato
David Bongiorno
Sergio Indelicato
Leopoldo Ceraulo
Ernesto Tranchina
Giuseppe Avellone
Concetta Arcadipane
Filippo Giambartino
Halogenated Anesthetics Determination in Urine by SPME/GC/MS and Urine Levels Relationship Evaluation with Surgical Theatres Contamination
Journal of Analytical Methods in Chemistry
author_facet Serena Indelicato
David Bongiorno
Sergio Indelicato
Leopoldo Ceraulo
Ernesto Tranchina
Giuseppe Avellone
Concetta Arcadipane
Filippo Giambartino
author_sort Serena Indelicato
title Halogenated Anesthetics Determination in Urine by SPME/GC/MS and Urine Levels Relationship Evaluation with Surgical Theatres Contamination
title_short Halogenated Anesthetics Determination in Urine by SPME/GC/MS and Urine Levels Relationship Evaluation with Surgical Theatres Contamination
title_full Halogenated Anesthetics Determination in Urine by SPME/GC/MS and Urine Levels Relationship Evaluation with Surgical Theatres Contamination
title_fullStr Halogenated Anesthetics Determination in Urine by SPME/GC/MS and Urine Levels Relationship Evaluation with Surgical Theatres Contamination
title_full_unstemmed Halogenated Anesthetics Determination in Urine by SPME/GC/MS and Urine Levels Relationship Evaluation with Surgical Theatres Contamination
title_sort halogenated anesthetics determination in urine by spme/gc/ms and urine levels relationship evaluation with surgical theatres contamination
publisher Hindawi Limited
series Journal of Analytical Methods in Chemistry
issn 2090-8865
2090-8873
publishDate 2014-01-01
description In this work, a new sensitive analytical method has been developed and evaluated for the determination of the most commonly used gaseous anesthetics, desflurane, sevoflurane, and this latter’s hepatic metabolite hexafluoroisopropanol (HFIP) in the urine. In addition, an evaluation of anesthetics exposition on the urine levels of a small population of surgical operators has been performed and results are briefly discussed.
url http://dx.doi.org/10.1155/2014/753237
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