New tricks of well-known aminoazoles in isocyanide-based multicomponent reactions and antibacterial activity of the compounds synthesized

New tricks of well-known aminoazoles in isocyanide-based multicomponent reactions and antibacterial activity of the compounds synthesized

The well-known aminoazoles, 3-amino-5-methylisoxazole and 5-amino-N-aryl-1H-pyrazole-4-carboxamides, were studied as an amine component in Ugi and Groebke–Blackburn–Bienaymé multicomponent reactions. The first example of an application of aminoazoles in an Ugi four-component reaction was discovered...

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Bibliographic Details
Main Authors: Maryna V. Murlykina, Maryna N. Kornet, Sergey M. Desenko, Svetlana V. Shishkina, Oleg V. Shishkin, Aleksander A. Brazhko, Vladimir I. Musatov, Erik V. Van der Eycken, Valentin A. Chebanov
Format: Article
Language:English
Published: Beilstein-Institut 2017-05-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
3-amino-5-methylisoxazole
5-amino-N-aryl-1H-pyrazole-4-carboxamides
antibacterial activity
Groebke–Blackburn–Bienaymé reaction
isocyanide Ugi reaction
Online Access:https://doi.org/10.3762/bjoc.13.104

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