Exosomes Derived From Adipose-Derived Mesenchymal Stem Cells Ameliorate Radiation-Induced Brain Injury by Activating the SIRT1 Pathway

Exosomes Derived From Adipose-Derived Mesenchymal Stem Cells Ameliorate Radiation-Induced Brain Injury by Activating the SIRT1 Pathway

ObjectiveStudies have shown that the therapeutic effects of mesenchymal stem cells (MSCs) are mediated in a paracrine manner, mainly through extracellular vesicles such as exosomes. Here, we designed a study to investigate whether exosomes derived from adipose-derived mesenchymal stem cells (ADMSC-E...

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Bibliographic Details
Main Authors: Mengdong Liu, Yunshu Yang, Bin Zhao, Yuefan Yang, Jing Wang, Kuo Shen, Xuekang Yang, Dahai Hu, Guoxu Zheng, Juntao Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
radiation
brain injury
exosomes
mesenchymal stem cells
oxidative stress
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.693782/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.693782/full

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