Decreased STEC shedding by cattle following passive and active vaccination based on recombinant Escherichia coli Shiga toxoids

Decreased STEC shedding by cattle following passive and active vaccination based on recombinant Escherichia coli Shiga toxoids

Abstract The principal virulence factor of Shiga toxin (Stx)-producing Escherichia coli (STEC), the eponymous Stx, modulates cellular immune responses in cattle, the primary STEC reservoir. We examined whether immunization with genetically inactivated recombinant Shiga toxoids (rStx1MUT/rStx2MUT) in...

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Bibliographic Details
Main Authors: Nadine Schmidt, Stefanie A. Barth, Jana Frahm, Ulrich Meyer, Sven Dänicke, Lutz Geue, Christian Menge
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Veterinary Research
Online Access:http://link.springer.com/article/10.1186/s13567-018-0523-0

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http://link.springer.com/article/10.1186/s13567-018-0523-0

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