Deep sequencing of the T cell receptor visualizes reconstitution of T cell immunity in mogamulizumab-treated adult T cell leukemia

Deep sequencing of the T cell receptor visualizes reconstitution of T cell immunity in mogamulizumab-treated adult T cell leukemia

Although the anti-CCR4 antibody mogamulizumab (moga) shows striking antitumor activity against adult T cell leukemia (ATL), it can also cause fatal immunological pathology such as severe skin rash and graft-versus-host disease, which might be attributed to depletion of CCR4+ regulatory T cells. We p...

Full description

Bibliographic Details
Main Authors:	Takero Shindo, Kazutaka Kitaura, Hiroshi Ureshino, Kazuharu Kamachi, Masaharu Miyahara, Kazuko Doi, Tatsuro Watanabe, Eisaburo Sueoka, Tadasu Shin-I, Ryuji Suzuki, Shinya Kimura
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2018-03-01
Series:	OncoImmunology
Subjects:	adult t cell leukemia mogamulizumab t cell receptor immune reconstitution next generation sequencing
Online Access:	http://dx.doi.org/10.1080/2162402X.2017.1405204

Similar Items

Mogamulizumab: a new tool for management of cutaneous T-cell lymphoma
by: Ollila TA, et al.
Published: (2019-02-01)

Successful Treatment of Erythrodermic Mycosis Fungoides with Mogamulizumab Followed by Etoposide Monotherapy
by: Taku Fujimura, et al.
Published: (2018-01-01)

Quantitatively immunological characterization of mogamulizumab skin disorders in ATL patients
by: Asahi Ito, et al.
Published: (2019-08-01)

Dupilumab as a therapy option for treatment refractory mogamulizumab-associated rash
by: Nicholas A. Trum, BS, et al.
Published: (2021-08-01)

Impressive continuous complete response after mogamulizumab in a heavily pre-treated Sézary syndrome patient
by: Pier Luigi Zinzani, et al.
Published: (2020-06-01)

Mogamulizumab-induced interface dermatitis drug rash treated successfully with methotrexate and extracorporeal photopheresis in a patient with Sézary syndrome
by: Ilana D. Breen, BS, et al.
Published: (2021-03-01)

Spotlight on Mogamulizumab-Kpkc for Use in Adults with Relapsed or Refractory Mycosis Fungoides or Sézary Syndrome: Efficacy, Safety, and Patient Selection
by: Blackmon AL, et al.
Published: (2020-09-01)

Risk of hepatitis B reactivation and cytomegalovirus related infections with Mogamulizumab: A retrospective study of international pharmacovigilance database
by: Shuai Wang, et al.
Published: (2020-11-01)

Safety and efficacy profile of mogamulizumab (Poteligeo) in the treatment of cancers: an update evidence from 14 studies
by: Ting Zhang, et al.
Published: (2021-05-01)

A phase Ib study of utomilumab (PF-05082566) in combination with mogamulizumab in patients with advanced solid tumors
by: Ezra E. W. Cohen, et al.
Published: (2019-12-01)

A Cell Adhesion-Based Reconstitution Method for Studying Cell Polarity
by: Christopher A. Johnston
Published: (2020-10-01)

Rituximab and Fibrillary Glomerulonephritis: Interest of B Cell Reconstitution Monitoring
by: Claire Leibler, et al.
Published: (2018-11-01)

Corrigendum: A Cell Adhesion-Based Reconstitution Method for Studying Cell Polarity
by: Christopher A. Johnston
Published: (2021-06-01)

Monitoring of pathogen-specific T-cell immune reconstitution after allogeneic hematopoietic stem cell transplantation
by: Shigeo eFuji, et al.
Published: (2013-09-01)

An Unconventional View of T Cell Reconstitution After Allogeneic Hematopoietic Cell Transplantation
by: Hana Andrlová, et al.
Published: (2021-02-01)

Reconstitution of T Cell Subsets Following Allogeneic Hematopoietic Cell Transplantation
by: Linde Dekker, et al.
Published: (2020-07-01)

Influence of KIR and NK Cell Reconstitution in the Outcomes of Hematopoietic Stem Cell Transplantation
by: Fei Gao, et al.
Published: (2020-09-01)

Long-term immune reconstitution and T cell repertoire analysis after autologous hematopoietic stem cell transplantation in systemic sclerosis patients
by: Dominique Farge, et al.
Published: (2017-01-01)

Comparison of immune reconstitution after allogeneic vs. autologous stem cell transplantation in 182 pediatric recipients
by: V. Wiegering, et al.
Published: (2017-03-01)

Mutual Interference between Cytomegalovirus and Reconstitution of Protective Immunity after Hematopoietic Cell Transplantation
by: Matthias J. Reddehase
Published: (2016-08-01)

Reconstitution of self-organizing protein gradients as spatial cues in cell-free systems
by: Katja Zieske, et al.
Published: (2014-10-01)

Reconstitution of the complete rupture in musculotendinous junction using skeletal muscle-derived multipotent stem cell sheet-pellets as a “bio-bond”
by: Hiroyuki Hashimoto, et al.
Published: (2016-07-01)

B Cell Reconstitution and Influencing Factors After Hematopoietic Stem Cell Transplantation in Children
by: Nicolaas G. van der Maas, et al.
Published: (2019-04-01)

Concise Review: Boosting T‐Cell Reconstitution Following Allogeneic Transplantation—Current Concepts and Future Perspectives
by: Laura Simons, et al.
Published: (2019-07-01)

Ability of reconstituted high density lipoproteins to inhibit cytokine-induced expression of vascular cell adhesion molecule-1 in human umbilical vein endothelial cells
by: Paul W. Baker, et al.
Published: (1999-02-01)

IL-2 and Anti-TGF-β Promote NK Cell Reconstitution and Anti-tumor Effects after Syngeneic Hematopoietic Stem Cell Transplantation
by: Maite Alvarez, et al.
Published: (2020-10-01)

How to improve immune reconstitution in allogeneic hematopoietic stem cell transplantation?
Published: (2015)

A quantitative hematopoietic stem cell reconstitution protocol: Accounting for recipient variability, tissue distribution and cell half-lives
by: Smrithi Rajendiran, et al.
Published: (2021-01-01)

Improved Relapse-Free Survival in Patients With High Natural Killer Cell Doses in Grafts and During Early Immune Reconstitution After Allogeneic Stem Cell Transplantation
by: Lia Minculescu, et al.
Published: (2020-05-01)

Chemotherapy-induced niche perturbs hematopoietic reconstitution in B-cell acute lymphoblastic leukemia
by: Chao Tang, et al.
Published: (2018-08-01)

Recent Advances in Therapeutic Approaches for Adult T-cell Leukemia/Lymphoma
by: Koji Kato, et al.
Published: (2015-12-01)

High Activation of γδ T Cells and the γδ2pos T-Cell Subset Is Associated With the Onset of Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome, ANRS 12153 CAPRI NK
by: Polidy Pean, et al.
Published: (2019-08-01)

Long-term expansion of directly reprogrammed keratinocyte-like cells and in vitro reconstitution of human skin
by: Jie Zheng, et al.
Published: (2020-04-01)

Pneumocystis pneumonia associated with peripheral lymphocytosis in angioimmunoblastic T-cell lymphoma, resembling immune reconstitution syndrome
by: Chiharu Tabata
Published: (2017-10-01)

Ovine Hair Follicle Stem Cells Derived from Single Vibrissae Reconstitute Haired Skin
by: Huishan Zhang, et al.
Published: (2015-08-01)

Development of LT-HSC-Reconstituted Non-Irradiated NBSGW Mice for the Study of Human Hematopoiesis In Vivo
by: George Adigbli, et al.
Published: (2021-03-01)

Modeling Influencing Factors in B-Cell Reconstitution After Hematopoietic Stem Cell Transplantation in Children
by: Nicolaas G. van der Maas, et al.
Published: (2021-05-01)

Naive and Stem Cell Memory T Cell Subset Recovery Reveals Opposing Reconstitution Patterns in CD4 and CD8 T Cells in Chronic Graft vs. Host Disease
by: Maria V. Soares, et al.
Published: (2019-03-01)

Immune Reconstitution in the Aging Host: Opportunities for Mechanism-Based Therapy in Allogeneic Hematopoietic Cell Transplantation
by: Richard J. Lin, et al.
Published: (2021-04-01)

Mechanisms of T Cell Reconstitution Following Lymphoablation in TransplantationAnd Description of a Novel Protective Role for T Cells in Epilepsy
by: Ayasoufi, Katayoun
Published: (2017)

Cannot write session to /tmp/vufind_sessions/sess_7imat4musa157bihl7d0opln5i