Role of Pancreatic Transcription Factors in Maintenance of Mature β-Cell Function

A variety of pancreatic transcription factors including PDX-1 and MafA play crucial roles in the pancreas and function for the maintenance of mature β-cell function. However, when β-cells are chronically exposed to hyperglycemia, expression and/or activities of such transcription factors are reduced...

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Bibliographic Details
Main Authors: Hideaki Kaneto, Taka-aki Matsuoka
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/16/3/6281