An Animal Model Using Metallic Ions to Produce Autoimmune Nephritis

Autoimmune nephritis triggered by metallic ions was assessed in a Long-Evans rat model. The parameters evaluated included antinuclear autoantibody production, kidney damage mediated by immune complexes detected by immunofluorescence, and renal function tested by retention of nitrogen waste products...

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Bibliographic Details
Main Authors: Roxana Ramírez-Sandoval, Nayeli Luévano-Rodríguez, Mayra Rodríguez-Rodríguez, María Elena Pérez-Pérez, Sergio Saldívar-Elias, Reinaldo Gurrola-Carlos, Esperanza Avalos-Díaz, Juan José Bollain-y-Goytia, Rafael Herrera-Esparza
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2015/269610