Burkholderia mallei and Burkholderia pseudomallei stimulate differential inflammatory responses from human alveolar type II cells (ATII) and macrophages.

Burkholderia mallei and Burkholderia pseudomallei stimulate differential inflammatory responses from human alveolar type II cells (ATII) and macrophages.

Alveolar type II pneumocytes (ATII) and alveolar macrophages (AM) play a crucial role in the lung’s innate immune response. Burkholderia pseudomallei (BP) and Burkholderia mallei (BM) are facultative Gram-negative bacilli that cause melioidosis and glanders, respectively. The inhalation of these p...

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Bibliographic Details
Main Authors: Richard eLu, Vsevolod ePopov, Jignesh ePatel, Tonyia eEaves-Pyles
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Burkholderia
Cytokines
Epithelial Cells
Macrophages
Toll-like receptor
alveoli
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2012.00165/full

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