Investigations into the Antibacterial Activity of the Silver-Based Antibiotic Drug Candidate SBC3

Investigations into the Antibacterial Activity of the Silver-Based Antibiotic Drug Candidate SBC3

The synthesis of N-heterocyclic carbene (NHC) silver(I) acetate complexes with varying lipophilic benzyl-substituents at the 1 and 3 positions starting from 4,5-diphenylimidazole, opened a new class of antibiotic drug candidates. These NHC-silver(I) acetate derivatives exhibit interesting structural...

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Bibliographic Details
Main Authors: Matthias Tacke, Bettina Schaible, Siddappa Patil, Francesca Paradisi, Frauke Hackenberg, Claire Healy, Stephen V. Gordon, Michael A. Sharkey, James P. O'Gara
Format: Article
Language:English
Published: MDPI AG 2012-11-01
Series:Antibiotics
Subjects:
silver
N-heterocyclic carbene
MRSA
Online Access:http://www.mdpi.com/2079-6382/1/1/25

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