Increased THEMIS First Exon Usage in CD4+ T-Cells Is Associated with a Genotype that Is Protective against Multiple Sclerosis.

Increased THEMIS First Exon Usage in CD4+ T-Cells Is Associated with a Genotype that Is Protective against Multiple Sclerosis.

Multiple sclerosis is an autoimmune disease of the central nervous system. Genome wide association studies have identified over 100 common variants associated with multiple sclerosis, the majority of which implicate immunologically relevant genes, particularly those involved in T-cell development. S...

Full description

Bibliographic Details
Main Authors: Jessica L Davies, Sara Thompson, Harpreet Kaur-Sandhu, Stephen Sawcer, Alasdair Coles, Maria Ban, Joanne Jones
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4954697?pdf=render

Internet

http://europepmc.org/articles/PMC4954697?pdf=render

Similar Items