Age-Related Loss of Cohesion: Causes and Effects

Aneuploidy is a leading genetic cause of birth defects and lower implantation rates in humans. Most errors in chromosome number originate from oocytes. Aneuploidy in oocytes increases with advanced maternal age. Recent studies support the hypothesis that cohesion deterioration with advanced maternal...

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Bibliographic Details
Main Authors: Jin-Mei Cheng, Yi-Xun Liu
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:International Journal of Molecular Sciences
Subjects:
age
Online Access:https://www.mdpi.com/1422-0067/18/7/1578