Dietary geranylgeraniol can limit the activity of pitavastatin as a potential treatment for drug-resistant ovarian cancer

Abstract Pre-clinical and retrospective studies of patients using statins to reduce plasma cholesterol have suggested that statins may be useful to treat cancer. However, prospective clinical trials have yet to demonstrate significant efficacy. We have previously shown that this is in part because a...

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Bibliographic Details
Main Authors: Elizabeth de Wolf, Marwan Ibrahim Abdullah, Stefanie M. Jones, Karen Menezes, Darren M. Moss, Falko P. Drijfhout, Sarah R. Hart, Clare Hoskins, Euan A. Stronach, Alan Richardson
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-05595-4