Local immune and microbiological responses to mucosal administration of a Liposome-TLR agonist immunotherapeutic in dogs

Local immune and microbiological responses to mucosal administration of a Liposome-TLR agonist immunotherapeutic in dogs

Abstract Background Non-specific immunotherapeutics have been evaluated previously in dogs, primarily for cancer treatment. However, there remains a need for a more broadly targeted, general purpose immunotherapeutic capable of activating innate immune defenses for non-specific protection or early t...

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Bibliographic Details
Main Authors: William Wheat, Lyndah Chow, Alana Kuzmik, Sirikul Soontararak, Jade Kurihara, Michael Lappin, Steven Dow
Format: Article
Language:English
Published: BMC 2019-09-01
Series:BMC Veterinary Research
Subjects:
Cytokine
T cells
Monocytes
Microbiome
Immunity
Immunotherapy
Online Access:http://link.springer.com/article/10.1186/s12917-019-2073-8

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