Prediction of Human Induced Pluripotent Stem Cell Cardiac Differentiation Outcome by Multifactorial Process Modeling

Prediction of Human Induced Pluripotent Stem Cell Cardiac Differentiation Outcome by Multifactorial Process Modeling

Human cardiomyocytes (CMs) have potential for use in therapeutic cell therapy and high-throughput drug screening. Because of the inability to expand adult CMs, their large-scale production from human pluripotent stem cells (hPSC) has been suggested. Significant improvements have been made in underst...

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Bibliographic Details
Main Authors: Bianca Williams, Wiebke Löbel, Ferdous Finklea, Caroline Halloin, Katharina Ritzenhoff, Felix Manstein, Samira Mohammadi, Mohammadjafar Hashemi, Robert Zweigerdt, Elizabeth Lipke, Selen Cremaschi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
machine learning
classification
feature selection
human induced pluripotent stem cells
cardiomyocytes
directed differentiation
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00851/full

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