Pro-inflammatory signaling by IL-10 and IL-22: bad habit stirred up by interferons ?

Interleukin (IL)-10 and IL-22 are key members of the IL-10 cytokine family that share characteristic properties such as defined structural features, usage of IL-10R2 as one receptor chain, and activation of signal transducer and activator of transcription (STAT)-3 as dominant signaling mode. IL-10,...

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Bibliographic Details
Main Author: Heiko eMühl
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-02-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00018/full