MIF mediates bladder pain, not inflammation, in cyclophosphamide cystitis

Macrophage migration inhibitory factor (MIF), a proinflammatory mediator, is recognized as a player in inflammatory and neuropathic pain. Cyclophosphamide (CYP) results in bladder inflammation and pain and it’s a frequently used animal model of interstitial cystitis/bladder pain syndrome (IC/BPS). B...

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Bibliographic Details
Main Authors: Fei Ma, Dimitrios E. Kouzoukas, Katherine L. Meyer-Siegler, David E. Hunt, Lin Leng, Richard Bucala, Pedro L. Vera
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Cytokine: X
Online Access:http://www.sciencedirect.com/science/article/pii/S2590153219300023