Cytokine Levels in Inner Ear Fluid of Young and Aged Mice as Molecular Biomarkers of Noise-Induced Hearing Loss

Cytokine Levels in Inner Ear Fluid of Young and Aged Mice as Molecular Biomarkers of Noise-Induced Hearing Loss

Sensorineural hearing loss (SNHL) is the most common sensory deficit worldwide, frequently caused by noise trauma and aging, with inflammation being implicated in both pathologies. Here, we provide the first direct measurements of proinflammatory cytokines in inner ear fluid, perilymph, of adolescen...

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Bibliographic Details
Main Authors: Lukas D. Landegger, Sasa Vasilijic, Takeshi Fujita, Vitor Y. Soares, Richard Seist, Lei Xu, Konstantina M. Stankovic
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Neurology
Subjects:
perilymph
noise-induced hearing loss
cytokines
CXCL1
DARC
age-related hearing loss
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.00977/full

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