MIM-Deficient Mice Exhibit Anatomical Changes in Dendritic Spines, Cortex Volume and Brain Ventricles, and Functional Changes in Motor Coordination and Learning

MIM-Deficient Mice Exhibit Anatomical Changes in Dendritic Spines, Cortex Volume and Brain Ventricles, and Functional Changes in Motor Coordination and Learning

In this study, we performed a comprehensive behavioral and anatomical analysis of the Missing in Metastasis (Mtss1/MIM) knockout (KO) mouse brain. We also analyzed the expression of MIM in different brain regions at different ages. MIM is an I-BAR containing membrane curving protein, shown to be inv...

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Bibliographic Details
Main Authors: Rimante Minkeviciene, Iryna Hlushchenko, Anaïs Virenque, Lauri Lahti, Pushpa Khanal, Tuomas Rauramaa, Arto Koistinen, Ville Leinonen, Francesco M. Noe, Pirta Hotulainen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Molecular Neuroscience
Subjects:
dendritic spines
brain ventricles
learning
motor coordination
anxiety
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2019.00276/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2019.00276/full

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