Molecular markers of anti-malarial drug resistance in Central, West and East African children with severe malaria

Molecular markers of anti-malarial drug resistance in Central, West and East African children with severe malaria

Abstract Background The Plasmodium falciparum multidrug resistance 1 (PfMDR1), P. falciparum Ca2+-ATPase (PfATP6) and Kelch-13 propeller domain (PfK13) loci are molecular markers of parasite susceptibility to anti-malarial drugs. Their frequency distributions were determined in the isolates collecte...

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Bibliographic Details
Main Authors: Christian N. Nguetse, Ayola Akim Adegnika, Tsiri Agbenyega, Bernhards R. Ogutu, Sanjeev Krishna, Peter G. Kremsner, Thirumalaisamy P. Velavan
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Malaria Journal
Subjects:
Malaria
P. falciparum
Pfmdr1
Pfatp6
Pfk13
Anti-malarial drugs
Online Access:http://link.springer.com/article/10.1186/s12936-017-1868-y

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