Bacteriophages M13 and T4 Increase the Expression of Anchorage-Dependent Survival Pathway Genes and Down Regulate Androgen Receptor Expression in LNCaP Prostate Cell Line

Bacteriophages M13 and T4 Increase the Expression of Anchorage-Dependent Survival Pathway Genes and Down Regulate Androgen Receptor Expression in LNCaP Prostate Cell Line

Wild-type or engineered bacteriophages have been reported as therapeutic agents in the treatment of several types of diseases, including cancer. They might be used either as naked phages or as carriers of antitumor molecules. Here, we evaluate the role of bacteriophages M13 and T4 in modulating the...

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Bibliographic Details
Main Authors: Swapnil Ganesh Sanmukh, Nilton José dos Santos, Caroline Nascimento Barquilha, Maira Smaniotto Cucielo, Márcio de Carvalho, Patricia Pintor dos Reis, Flávia Karina Delella, Hernandes F. Carvalho, Sérgio Luis Felisbino
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Viruses
Subjects:
prostate cancer
gene expression
integrin
bacteriophage
nanoparticle
Online Access:https://www.mdpi.com/1999-4915/13/9/1754

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