Additive effect by combination of Akt inhibitor, MK-2206, and PDGFR inhibitor, tyrphostin AG 1296, in suppressing anaplastic thyroid carcinoma cell viability and motility

Huan-yong Che, Hang-yuan Guo, Xu-wei Si, Qiao-ying You, Wei-ying Lou Shaoxing People's Hospital, Shaoxing Hospital of Zhejiang University, Shaoxing, Zhejiang, People's Republic of China Abstract: The phosphatidylinositol-3-kinase/Akt pathway and receptor tyrosine kinases regulate m...

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Bibliographic Details
Main Authors: Che HY, Guo HY, Si XW, You QY, Lou WY
Format: Article
Language:English
Published: Dove Medical Press 2014-03-01
Series:OncoTargets and Therapy
Online Access:http://www.dovepress.com/additive-effect-by-combination-of-akt-inhibitor-mk-2206-and-pdgfr-inhi-a16112