Synergistic roles of p53 and HIF1α in human renal cell carcinoma-cell apoptosis responding to the inhibition of mTOR and MDM2 signaling pathways

Synergistic roles of p53 and HIF1α in human renal cell carcinoma-cell apoptosis responding to the inhibition of mTOR and MDM2 signaling pathways

Qing-jun Liu,* Hong-liang Shen,* Jun Lin, Xiu-hong Xu, Zheng-guo Ji, Xiao Han, Dong-hao Shang, Pei-qian YangDepartment of Urology Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, People’s Republic of China*These authors contributed equally to this workInt...

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Bibliographic Details
Main Authors: Liu QJ, Shen HL, Lin J, Xu XH, Ji ZG, Han X, Shang DH, Yang PQ
Format: Article
Language:English
Published: Dove Medical Press 2016-02-01
Series:Drug Design, Development and Therapy
Subjects:
renal cell carcinoma
mTOR
MDM2
p53
HIF1α
apoptosis.
Online Access:https://www.dovepress.com/synergistic-roles-of-p53-and-hif1alpha-in-human-renal-cell-carcinoma-c-peer-reviewed-article-DDDT

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https://www.dovepress.com/synergistic-roles-of-p53-and-hif1alpha-in-human-renal-cell-carcinoma-c-peer-reviewed-article-DDDT

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