Dysregulated Intrahepatic CD4+ T-Cell Activation Drives Liver Inflammation in Ileitis-Prone SAMP1/YitFc MiceSummary

Background & Aims: Liver inflammation is a common extraintestinal manifestation of inflammatory bowel disease (IBD), but whether liver involvement is a consequence of a primary intestinal defect or results from alternative pathogenic processes remains unclear. Therefore, we sought to determine t...

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Bibliographic Details
Main Authors: Sara Omenetti, Marco Brogi, Wendy A. Goodman, Colleen M. Croniger, Saada Eid, Alex Y. Huang, Giacomo Laffi, Tania Roskams, Fabio Cominelli, Massimo Pinzani, Theresa T. Pizarro
Format: Article
Language:English
Published: Elsevier 2015-07-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X15001010