Functional profiling reveals critical role for miRNA in differentiation of human mesenchymal stem cells.

BACKGROUND:Mesenchymal stem (MS) cells are excellent candidates for cell-based therapeutic strategies to regenerate injured tissue. Although human MS cells can be isolated from bone marrow and directed to differentiate by means of an osteogenic pathway, the regulation of cell-fate determination is n...

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Bibliographic Details
Main Authors: Angela Schoolmeesters, Teresa Eklund, Devin Leake, Annaleen Vermeulen, Queta Smith, Shelley Force Aldred, Yuriy Fedorov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2680014?pdf=render