CD37 in B Cell Derived Tumors—More than Just a Docking Point for Monoclonal Antibodies

CD37 in B Cell Derived Tumors—More than Just a Docking Point for Monoclonal Antibodies

CD37 is a tetraspanin expressed prominently on the surface of B cells. It is an attractive molecular target exploited in the immunotherapy of B cell-derived lymphomas and leukemia. Currently, several monoclonal antibodies targeting CD37 as well as chimeric antigen receptor-based immunotherapies are...

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Bibliographic Details
Main Authors: Malgorzata Bobrowicz, Matylda Kubacz, Aleksander Slusarczyk, Magdalena Winiarska
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
CD37
tetraspanin
non-Hodgkin lymphoma
chronic lymphocytic leukemia
immunotherapy
monoclonal antibodies
Online Access:https://www.mdpi.com/1422-0067/21/24/9531

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