Sorafenib - induced thyroiditis in patient with a relapse of acute myelomonocytic leukemia with FLT3-ITD mutation

Sorafenib - induced thyroiditis in patient with a relapse of acute myelomonocytic leukemia with FLT3-ITD mutation

Sorafenib has been used in acute myeloid leukemias with FLT3-ITD mutation improving the outcomes. However the high incidence of treatment - emergent adverse event may be associated with treatment using sorafenib with cytotoxic chemotherapy. We have reported a case of severe thyroiditis in patient wi...

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Bibliographic Details
Main Authors: Ya B Balzhanova, E N Parovichnikova, A N Sokolov, V V Ryzhko, M A Samtsova, E O Gribanova
Format: Article
Language:Russian
Published: "Consilium Medicum" Publishing house 2019-08-01
Series:Терапевтический архив
Subjects:
sorafenib
thyroiditis
acute myeloid leukemia
relapse
flt3-itd mutation
Online Access:https://ter-arkhiv.ru/0040-3660/article/viewFile/33640/pdf
Description
Summary:Sorafenib has been used in acute myeloid leukemias with FLT3-ITD mutation improving the outcomes. However the high incidence of treatment - emergent adverse event may be associated with treatment using sorafenib with cytotoxic chemotherapy. We have reported a case of severe thyroiditis in patient with a relapse of acute myelomonocytic leukemia.
ISSN:0040-3660
2309-5342

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