TRPV4 inhibition prevents increased water diffusion and blood-retina barrier breakdown in the retina of streptozotocin-induced diabetic mice.

TRPV4 inhibition prevents increased water diffusion and blood-retina barrier breakdown in the retina of streptozotocin-induced diabetic mice.

A better understanding of the molecular and cellular mechanisms involved in retinal hydro-mineral homeostasis imbalance during diabetic macular edema (DME) is needed to gain insights into retinal (patho-)physiology that will help elaborate innovative therapies with lower health care costs. Transient...

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Bibliographic Details
Main Authors: Maricruz Orduña Ríos, Ramsés Noguez Imm, Nicole Marilú Hernández Godínez, Ana María Bautista Cortes, Dayana Deyanira López Escalante, Wolfgang Liedtke, Atáulfo Martínez Torres, Luis Concha, Stéphanie Thébault
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0212158

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