The C-terminal of CASY-1/Calsyntenin regulates GABAergic synaptic transmission at the Caenorhabditis elegans neuromuscular junction.

The C. elegans ortholog of mammalian calsyntenins, CASY-1, is an evolutionarily conserved type-I transmembrane protein that is highly enriched in the nervous system. Mammalian calsyntenins are strongly expressed at inhibitory synapses, but their role in synapse development and function is still elus...

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Bibliographic Details
Main Authors: Shruti Thapliyal, Amruta Vasudevan, Yongming Dong, Jihong Bai, Sandhya P Koushika, Kavita Babu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5864096?pdf=render