Proteins are potent biomarkers to detect colon cancer progression

Proteins are potent biomarkers to detect colon cancer progression

Colon cancer is the most common type of cancer and major cause of death worldwide. The detection of colon cancer is difficult in early stages. However, the secretory proteins have been used as ideal biomarker for the detection of colon cancer progress in cancer patients. Serum/tissue protein express...

Full description

Bibliographic Details
Main Authors: Palaniselvam Kuppusamy, Natanamurugaraj Govindan, Mashitah M. Yusoff, Solachuddin J.A. Ichwan
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Saudi Journal of Biological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1319562X14001247
id doaj-b98f5192882b48fd9e06e9f11cd22a5c
record_format Article
spelling doaj-b98f5192882b48fd9e06e9f11cd22a5c2020-11-24T21:00:48ZengElsevierSaudi Journal of Biological Sciences1319-562X2017-09-0124612121221Proteins are potent biomarkers to detect colon cancer progressionPalaniselvam Kuppusamy0Natanamurugaraj Govindan1Mashitah M. Yusoff2Solachuddin J.A. Ichwan3Mammalian Cell Technology Laboratory, Faculty of Industrial Sciences and Technology, Universiti Malaysia Pahang, Lebuhraya Tun Razak 26300, Gambang, Kuantan, Pahang, Malaysia; Corresponding author. Tel.: +60 142918824, +60 95492465 (office); fax: +60 95492766.Mammalian Cell Technology Laboratory, Faculty of Industrial Sciences and Technology, Universiti Malaysia Pahang, Lebuhraya Tun Razak 26300, Gambang, Kuantan, Pahang, MalaysiaMammalian Cell Technology Laboratory, Faculty of Industrial Sciences and Technology, Universiti Malaysia Pahang, Lebuhraya Tun Razak 26300, Gambang, Kuantan, Pahang, MalaysiaKulliyyah of Dentistry, International Islamic University Malaysia, Bandar Indera Mahkota 125200, Kuantan, Pahang, MalaysiaColon cancer is the most common type of cancer and major cause of death worldwide. The detection of colon cancer is difficult in early stages. However, the secretory proteins have been used as ideal biomarker for the detection of colon cancer progress in cancer patients. Serum/tissue protein expression could help general practitioners to identify colon cancer at earlier stages. By this way, we use the biomarkers to evaluate the anticancer drugs and their response to therapy in cancer models. Recently, the biomarker discovery is important in cancer biology and disease management. Also, many measurable specific molecular components have been studied in colon cancer therapeutics. The biomolecules are mainly DNA, RNA, metabolites, enzymes, mRNA, aptamers and proteins. Thus, in this review we demonstrate the important protein biomarker in colon cancer development and molecular identification of protein biomarker discovery. Keywords: Colon cancer, Biomarkers, Secretory proteins, Proteomic techniqueshttp://www.sciencedirect.com/science/article/pii/S1319562X14001247
collection DOAJ
language English
format Article
sources DOAJ
author Palaniselvam Kuppusamy
Natanamurugaraj Govindan
Mashitah M. Yusoff
Solachuddin J.A. Ichwan
spellingShingle Palaniselvam Kuppusamy
Natanamurugaraj Govindan
Mashitah M. Yusoff
Solachuddin J.A. Ichwan
Proteins are potent biomarkers to detect colon cancer progression
Saudi Journal of Biological Sciences
author_facet Palaniselvam Kuppusamy
Natanamurugaraj Govindan
Mashitah M. Yusoff
Solachuddin J.A. Ichwan
author_sort Palaniselvam Kuppusamy
title Proteins are potent biomarkers to detect colon cancer progression
title_short Proteins are potent biomarkers to detect colon cancer progression
title_full Proteins are potent biomarkers to detect colon cancer progression
title_fullStr Proteins are potent biomarkers to detect colon cancer progression
title_full_unstemmed Proteins are potent biomarkers to detect colon cancer progression
title_sort proteins are potent biomarkers to detect colon cancer progression
publisher Elsevier
series Saudi Journal of Biological Sciences
issn 1319-562X
publishDate 2017-09-01
description Colon cancer is the most common type of cancer and major cause of death worldwide. The detection of colon cancer is difficult in early stages. However, the secretory proteins have been used as ideal biomarker for the detection of colon cancer progress in cancer patients. Serum/tissue protein expression could help general practitioners to identify colon cancer at earlier stages. By this way, we use the biomarkers to evaluate the anticancer drugs and their response to therapy in cancer models. Recently, the biomarker discovery is important in cancer biology and disease management. Also, many measurable specific molecular components have been studied in colon cancer therapeutics. The biomolecules are mainly DNA, RNA, metabolites, enzymes, mRNA, aptamers and proteins. Thus, in this review we demonstrate the important protein biomarker in colon cancer development and molecular identification of protein biomarker discovery. Keywords: Colon cancer, Biomarkers, Secretory proteins, Proteomic techniques
url http://www.sciencedirect.com/science/article/pii/S1319562X14001247
work_keys_str_mv AT palaniselvamkuppusamy proteinsarepotentbiomarkerstodetectcoloncancerprogression
AT natanamurugarajgovindan proteinsarepotentbiomarkerstodetectcoloncancerprogression
AT mashitahmyusoff proteinsarepotentbiomarkerstodetectcoloncancerprogression
AT solachuddinjaichwan proteinsarepotentbiomarkerstodetectcoloncancerprogression
_version_ 1716778736288792576

Similar Items