Sirtuin 3 is essential for host defense against Mycobacterium abscessus infection through regulation of mitochondrial homeostasis

Sirtuin 3 is essential for host defense against Mycobacterium abscessus infection through regulation of mitochondrial homeostasis

The global incidence of Mycobacterium abscessus (Mabc), a rapidly growing nontuberculous mycobacterial strain that causes treatment-refractory pulmonary diseases, is increasing. Despite this, the host factors that allow for protection against infection are largely unknown. In this study, we found th...

Full description

Bibliographic Details
Main Authors: Young Jae Kim, Sang-Hee Lee, Sang Min Jeon, Prashanta Silwal, Ju-Young Seo, Bui Thi Bich Hanh, June-Woo Park, Jake Whang, Min Joung Lee, Jun Young Heo, Soon Ha Kim, Jin-Man Kim, Gyu Yong Song, Jichan Jang, Eun-Kyeong Jo
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Virulence
Subjects:
mycobacterium abscessus
sirtuin 3
mitochondrial reactive oxygen species
resveratrol
host-directed therapy
Online Access:http://dx.doi.org/10.1080/21505594.2020.1809961

Internet

http://dx.doi.org/10.1080/21505594.2020.1809961

Similar Items