Influence various combinations of salts of heavy metals on structural rearrangement of a myocardium of rats of mature age.

• Main Author: Pogorelova O. S.
• Format: Article
• Language: Russian
• Published: Ministry of Health of Ukraine. Dnipropetrovsk Medical Academy 2007-01-01
• Series: Морфологія
• Subjects: rat heart; heavy metals
• Online Access: http://www.morphology.dp.ua/_pub/MORPHO-2007-01-04/07possvm.pdf

The work purpose is studying of morphological features of a myocardium of mature rats in the conditions of ecology of northern regions Ukraine. In experiment 72 rats of monthly age who have been divided into four series on 18 animals in everyone have been used. The first series have compounded control rats. An animal of the second - the fourth series modelled conditions of ecology of northern regions Ukraine. Concentration of metals which introduced into a water ration was following: zinc (ZnSO) - 50 mg/l, copper - 5,0 mg/l (CuSо) and Ferri lactas - 20 mg/l; zinc - 50 mg/l, chrome - 10,0 mg/l and lead - 3mg/l; manganese - of 5,0 mg/l, lead - 3,0 mg/l and copper - 5,0 mg/l. At rats who received salts of copper, zinc and iron throughout 1 month, the non-uniform augmentation of dimensions CM was marked: in the same field of vision there were specified cages of the different dimensions (hypertrophied and the normal dimensions). At rats who received salts of zinc, chrome and lead throughout 3 months, marked infringement of orientation of muscular fibres, fields of their fragmenta-tion. In the studied fields of vision there was dystrophia CM: contours of cages indistinct, cytoplasm is non-uniformly im-bued, acinose, cross-section striation was not visualised by fields.