Activation of the cell stress kinase PKR in Alzheimer’s disease and human amyloid precursor protein transgenic mice
Accumulation of amyloid β peptides (Aβ) in the brain, which is a hallmark of Alzheimer’s disease (AD), is associated with progressive damage to neuronal processes resulting in extensive neuritic dystrophy. This process may contribute to cognitive decline, but it is not known how Aβ elicits neuritic...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2003-10-01
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| Series: | Neurobiology of Disease |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S096999610300086X |